A Commentary, Critical, Practical, and Explanatory on the Old and New Testaments, by Robert Jamieson, A.R. Fausset and David Brown  at sacred-texts.com
deu 28:1THE BLESSINGS FOR OBEDIENCE. (Deu. 28:1-68)
if thou shalt hearken diligently unto the voice of the Lord thy God--In this chapter the blessings and curses are enumerated at length, and in various minute details, so that on the first entrance of the Israelites into the land of promise, their whole destiny was laid before them, as it was to result from their obedience or the contrary.
deu 28:2all these blessings shall come on thee--Their national obedience was to be rewarded by extraordinary and universal prosperity.
deu 28:7flee before thee seven ways--that is, in various directions, as always happens in a rout.
deu 28:10called by the name of the Lord--That they are really and actually His people (Deu 14:1; Deu 26:18).
deu 28:11the Lord shall make thee plenteous in goods--Beside the natural capabilities of Canaan, its extraordinary fruitfulness was traceable to the special blessing of Heaven.
deu 28:12The Lord shall open unto thee his good treasure--The seasonable supply of the early and latter rain was one of the principal means by which their land was so uncommonly fruitful.
thou shalt lend unto many nations, and thou shalt not borrow--that is, thou shalt be in such affluent circumstances, as to be capable, out of thy superfluous wealth, to give aid to thy poorer neighbors.
deu 28:13the head, and not the tail--an Oriental form of expression, indicating the possession of independent power and great dignity and acknowledged excellence (Isa 9:14; Isa 19:15).
deu 28:15But . . . if thou wilt not hearken unto the voice of the Lord--Curses that were to follow them in the event of disobedience are now enumerated, and they are almost exact counterparts of the blessings which were described in the preceding context as the reward of a faithful adherence to the covenant.
deu 28:21pestilence--some fatal epidemic. There is no reason, however, to think that the plague, which is the great modern scourge of the East, is referred to.
deu 28:22a consumption--a wasting disorder; but the modern tuberculosis is almost unknown in Asia.
fever . . . inflammation . . . extreme burning--Fever is rendered "burning ague" (Lev 26:16), and the others mentioned along with it evidently point to those febrile affections which are of malignant character and great frequency in the East.
the sword--rather, "dryness"--the effect on the human body of such violent disorders.
blasting, and with mildew--two atmospheric influences fatal to grain.
deu 28:23heaven . . . brass . . . earth . . . iron--strong Oriental figures used to describe the effects of long-continued drought. This want of regular and seasonable rain is allowed by the most intelligent observers to be one great cause of the present sterility of Palestine.
deu 28:24the rain of thy land powder and dust--an allusion probably to the dreadful effects of tornadoes in the East, which, raising the sands in immense twisted pillars, drive them along with the fury of a tempest. These shifting sands are most destructive to cultivated lands; and in consequence of their encroachments, many once fertile regions of the East are now barren deserts.
deu 28:27the botch of Egypt--a troublesome eruption, marked by red pimples, to which, at the rising of the Nile, the Egyptians are subject.
emerods--fistulÃ&brvbr; or piles.
itch--the disease commonly known by that name; but it is far more malignant in the East than is ever witnessed in our part of the world.
deu 28:28madness, and blindness, and astonishment of heart--They would be bewildered and paralyzed with terror at the extent of their calamities.
deu 28:29thou shalt grope at noonday--a general description of the painful uncertainty in which they would live. During the Middle Ages the Jews were driven from society into hiding-places which they were afraid to leave, not knowing from what quarter they might be assailed and their children dragged into captivity, from which no friend could rescue, and no money ransom them.
deu 28:35the Lord shall smite thee in the knees, and in the legs--This is an exact description of elephantiasis, a horrible disease, something like leprosy, which attacks particularly the lower extremities.
deu 28:36The Lord shall bring thee, and thy king, &c.--This shows how widespread would be the national calamity; and at the same time how hopeless, when he who should have been their defender shared the captive fate of his subjects.
there shalt thou serve other gods, wood and stone--The Hebrew exiles, with some honorable exceptions, were seduced or compelled into idolatry in the Assyrian and Babylonish captivities (Jer 44:17-19). Thus, the sin to which they had too often betrayed a perverse fondness, a deep-rooted propensity, became their punishment and their misery.
deu 28:37And thou shalt become an astonishment, a proverb, and a byword, among all nations whither the Lord shall lead thee, &c.--The annals of almost every nation, for eighteen hundred years, afford abundant proofs that this has been, as it still is, the case--the very name of Jew being a universally recognized term for extreme degradation and wretchedness.
deu 28:49The Lord shall bring a nation against thee from far--the invasion of the Romans--"they came from far." The soldiers of the invading army were taken from France, Spain, and Britain--then considered "the end of the earth." Julius Severus, the commander, afterwards Vespasian and Hadrian, left Britain for the scene of contest. Moreover, the ensign on the standards of the Roman army was "an eagle"; and the dialects spoken by the soldiers of the different nations that composed that army were altogether unintelligible to the Jews.
deu 28:50A nation of fierce countenance--a just description of the Romans, who were not only bold and unyielding, but ruthless and implacable.
deu 28:51he shall eat the fruit of thy cattle, &c.--According to the Jewish historian, every district of the country through which they passed was strewn with the wrecks of their devastation.
deu 28:52he shall besiege thee . . . until thy high and fenced walls come down--All the fortified places to which the people betook themselves for safety were burnt or demolished, and the walls of Jerusalem itself razed to the ground.
deu 28:53And thou shalt eat the fruit of thine own body--(See Kg2 6:29; Lam 4:10). Such were the dreadful extremities to which the inhabitants during the siege were reduced that many women sustained a wretched existence by eating the flesh of their own children. Parental affection was extinguished, and the nearest relatives were jealously, avoided, lest they should discover and demand a share of the revolting viands.
deu 28:62ye shall be left few in number--There has been, ever since the destruction of Jerusalem, only an inconsiderable remnant of Jews existing in that land--aliens in the land of their fathers; and of all classes of the inhabitants they are the most degraded and miserable beings, dependent for their support on contributions from other lands.
deu 28:63ye shall be plucked from off the land--Hadrian issued a proclamation, forbidding any Jews to reside in Judea, or even to approach its confines.
deu 28:64the Lord shall scatter thee among all people--There is, perhaps, not a country in the world where Jews are not to be found. Who that looks on this condition of the Hebrews is not filled with awe, when he considers the fulfilment of this prophecy?
deu 28:68The Lord shall bring thee into Egypt again with ships--The accomplishment of this prediction took place under Titus, when, according to JOSEPHUS, multitudes of Jews were transported in ships to the land of the Nile, and sold as slaves. "Here, then, are instances of prophecies delivered above three thousand years ago; and yet, as we see, being fulfilled in the world at this very time; and what stronger proofs can we desire of the divine legation of Moses? How these instances may affect others I know not; but for myself, I must acknowledge, they not only convince but amaze and astonish me beyond expression; they are truly, as Moses foretold (Deu 28:45-46) they would be, 'a sign and a wonder for ever'" [BISHOP NEWTON].